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On November 2, 2026, the US Environmental Protection Agency (EPA) published a proposal in the Federal Register for significant new use rules (SNURs) covering certain chemicals under the Toxic Substances Control Act (TSCA).
The proposal would require companies to notify the EPA at least 90 days before manufacturing, importing or processing the covered chemicals for a significant new use, and to wait for the agency's review. The intended purpose is to allow assessment of potential environmental and health risks associated with those uses.

For manufacturers, importers and processors, the proposed notification period could affect the timing of plans involving a covered chemical and a significant new use. Businesses considering such uses may need to account for regulatory review before proceeding.
The measures remain a proposal, so their eventual effect will depend on the final rules, including which chemicals and uses they cover. The proposal does not establish that every use of the chemicals would be subject to the new notification requirement.
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